Sympathetic ganglionic blocking actions of homotaurine and hexamethonium
نویسندگان
چکیده
منابع مشابه
Experimental and clinical evaluation in man of hexamethonium (C6), a new ganglionic blocking agent.
In man, C6, a new ganglionic blocking agent (50 mg. intravenously) produced inhibition of the Valsalva, tiltback and cold pressor vasopressor responses. Marked increases in digital blood flow and skin temperature with inhibition of digital reflexes to "noxious" stimuli were consistently observed (room temperature 70 F.). The increase in skin temperature was greater and more lasting than followi...
متن کاملGanglionic Blocking Drugs and Nicotine
Transmission through autonomic ganglia is more complex than neurotransmission at the neuromuscular and postganglionic neuroeffector junctions and is subject to numerous pharmacological and physiological influences. In some ganglionic synapses, especially at parasympathetic ganglia, there is a simple presynaptic to postsynaptic cell relationship; in others, the presynaptic to postsynaptic cell r...
متن کاملThe influence of certain ganglionic blocking agents on neuromuscular transmission.
GANGLIONIC blockade was first used to produce controlled hypotension during surgery by Scurr (1951). This technique has since become generally accepted in anaesthetic practice. Ganglion blocking drugs now available include the methonium compounds and the short acting agents trimetaphan and homatropinium (Trophenium). There is no doubt that these drugs act selectively on the sympathetic ganglia,...
متن کاملThe Influence of Certain Ganglionic Blocking Agents on Neuromuscular Transmission
GANGLIONIC blockade was first used to produce controlled hypotension during surgery by Scurr (1951). This technique has since become generally accepted in anaesthetic practice. Ganglion blocking drugs now available include the methonium compounds and the short acting agents trimetaphan and homatropinium (Trophenium). There is no doubt that these drugs act selectively on the sympathetic ganglia,...
متن کاملUltraviolet light activates blocking actions of dantrolene on intracellular Ca2+ release in bullfrog sympathetic neurones.
Effects of dantrolene, a blocker of intracellular Ca2+ release, on the oscillation of the intracellular Ca2+ ([Ca2+]i) induced by caffeine were studied in bullfrog sympathetic ganglion cells, using a Fura-2 fluorescence technique. Dantrolene blocked the Ca2+ oscillation only in the cell illuminated by ultraviolet light (335-385 nm). Likewise, the blocking effects on rhythmic Ca(2+)-dependent hy...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 1971
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.67.564